In Kuwait, the historical benchmark for the Newcastle Disease virus dates back to the mid-20th century. The Kuwait 256 (Fowl/1968) strain is one of the most well-known regional isolates used worldwide in comparative molecular studies. This historic velogenic isolate confirmed that virulent lineages of the virus were actively circulating within the country’s early commercial or backyard poultry holdings as far back as 1968. Since then, PAAFR’s diagnostic surveillance has recorded both chronic persistence in live bird markets and non-commercial backyard flocks, as well as occasional epidemics in commercial operations.
The three main pathotypes of Newcastle Disease Virus (NDV) strains in birds are lentogenic (low virulence, mild/no symptoms), mesogenic (moderate virulence), and velogenic (very pathogenic, causing severe respiratory/nervous manifestations and significant mortality).